Loren Niklason interview

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  • Early Life and Education
    Partial Transcript: Okay so we're recording
    Synopsis: In this segment, Loren Niklason discusses his early life and education as well as his with tomosynthesis
    Keywords: bioengineering; Boeing; breast imaging; Harvard; medical physics; tomosynthesis; University of Alabama Birmingham; University of Michigan; University of Utah
  • Development of Breast Tomosynthesis pt. 1
    Partial Transcript: I applied for a patent
    Synopsis: Niklason discusses the early stages of breast tomosynthesis, starting from the patent in 1995, the stages of clinical trials, and then his work with General Electric and Hologic
    Keywords: 2D mammography; breast tomosynthesis; digital mammography; FDA; Federal Drug Administration; General Electric; Hologic; Jay Stein
  • Development of Breast Tomosynthesis pt. 2
    Partial Transcript: So by this time
    Synopsis: In continuing his discussion of breast tomosynthesis, Niklason explains the process of receiving FDA approval and publishing papers and studies on this technology
    Keywords: 3D Mammography; Europe; FDA; General Electric; JAMA; Journal of the American Medical Association; radiologists; Siemens; tomosynthesis
  • Hologic and Breast Tomosynthesis
    Partial Transcript: Well maybe I should
    Synopsis: Niklason details the ways in which Hologic worked to establish breast tomosynthesis, especially on account of the leadership of Jay Stein
    Keywords: C-View; Chris Ruth; FDA; General Electric; Hologic; Jay Stein; Siemens
  • Background on Tomosynthesis
    Partial Transcript: I was wondering
    Synopsis: In this segment, Niklason describes what tomosynthesis is and how is compares to standard mammography. He also discusses the 25-year process of this technology, from approval to fruition
    Keywords: breast cancer; General Electric; Harvard; Hologic; Jay Stein; mammography; x-ray
  • Tomosynthesis vs. Breast Tomosynthesis
    Partial Transcript: So I sort of
    Synopsis: Niklason discusses the difference between standard tomosynthesis imaging and breast tomosynthesis imaging, he also points to the development of the flat panel digital detector as a crucial breakthrough in this system
    Keywords: CT Scan; digital mammography; Flat Panel Digital Detector; General Electric; tomosynthesis
  • Advantages and Challenges of Tomosynthesis
    Partial Transcript: Sorry, I'm catching up
    Synopsis: In this segment, Niklason explains the advantages and unique nature of tomosynthesis as well as its challenges, especially in comparison to standard mammograms
    Keywords: CT imaging; Hologic; mammogram; radiologists; tomosynthesis; x-rays
  • Motivation for Working at Hologic/Early Years at Hologic
    Partial Transcript: So, did anything in particular
    Synopsis: Niklason talks about how he ended up working in the women's health field and how his relationship with Jay Stein led him to work for Hologic. He also discusses the early days at Hologic and his main responsibilities
    Keywords: Army Breast Cancer Research Program; Boston; breast imaging; Chicago; FDA; Hologic; Jay Stein; Radiological Society of North America; RSNA; University of Michigan; Waltham, MA
  • Convincing People to Adopt Tomosynthesis
    Partial Transcript: And then you said
    Synopsis: Niklason, in explaining his role of persuading professionals to use tomosynthesis, mentions that academic publications, clinical trials, and presentations were effective in convincing people to adopt this technology
    Keywords: FDA; JAMA; Journal of Radiology; Journal of the American Medical Association; mammogram; RSNA
  • Work with the FDA/Differences between U.S. and Europe
    Partial Transcript: So, if you don't mind
    Synopsis: In this segment, Niklason talks about his work with the FDA and other regulatory agencies, he also mentions the differences of working with tomosynthesis in the United States compared to Europe
    Keywords: CE Mark; China; FDA; Hologic; Japan; mammography; Massachusetts General Hospital; Oslo; tomosynthesis
  • Good vs. Bad Days/Tomosynthesis Mammographic Imaging
    Partial Transcript: Interesting. So what was
    Synopsis: In this segment, Niklason says what were some good and bad days working at Hologic and then goes into an explanation of the Tomosynthesis Mammographic Imaging Screening Trials (TMIST)
    Keywords: Boston; Hologic; invasive breast cancer; TMIST; tomosynthesis; Tomosynthesis Mammographic Imaging Screening Trial
  • Reflections on Career
    Partial Transcript: So what would you say
    Synopsis: In this final segment, Niklason reflects on his career with Hologic and mentions the most and least rewarding aspects of his career
    Keywords: FDA; Hologic; JAMA; Jay Stein; Journal of the American Medical Association; Tomosynthesis
Details
Title

Loren Niklason interview

Date Created

2020-08-26

Summary

In this interview, Loren Niklason discusses his role in developing breast tomosynthesis. Niklason walks through the system of tomosynthesis and how it was adapted for breast imaging. Niklason provides an in-depth explanation of breast tomosynthesis, how it differed from standard mammography, and the challenges of tomosynthesis. Niklason also shares the process of working with the FDA and other agencies throughout his time at Hologic.

Interviewee

Niklason, Loren, 1952-

Interviewer

Spohn, Benjamin

Associated Name (corporate)

Hologic (Firm)

Biographical Note

Loren Niklason (1952-) grew up in Utah and attended the University of Utah for his undergraduate education as well as a Master's degree and Ph.D in bioengineering. Following graduate school, Niklason worked a number of academic jobs, including work at the University of Michigan, Harvard, and the University of Alabama Birmingham. In 1995, Niklason applied for and was granted a patent for breast tomosynthesis. In 2006, Niklason joined Hologic and worked there to develop breast tomosynthesis and worked there until his retirement in 2016.

Subject(s)

Diagnostic imaging
Breast--Radiography
Medical technology
Bioengineering

Find all items with name(s)

Niklason, Loren, 1952-
Hologic (Firm)
Spohn, Benjamin

Genre

oral histories

Language

English

Type of resource

sound recording

Extent

1 WAV file. (01:29:34:00).

Repository

Audiovisual Collections and Digital Initiatives Department, Hagley Museum and Library

Original Collection

Hologic Medical Imaging oral histories (Accession 2020.201)

Finding Aid

https://findingaids.hagley.org/2020_201

Preferred Citation

[Description and dates], Hagley ID, Box/folder number, Hologic Medical Imaging oral histories (Accession 2020.201), Audiovisual Collections and Digital Initiatives Department, Hagley Museum and Library, Wilmington, DE 19807

Access Condition

Access to this item is provided for educational and research purposes only. The user assumes responsibility for obtaining permission from the copyright holder to publish or distribute this image. If you would like more information, please contact askhagley@hagley.org

Hagley ID

2020201_Niklason_Loren_20200826

PID

islandora:2661947

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